Today, I have the honor of publishing a piece by Professor Edward Shorter, PhD, FRSC.

Is Lithium the Drug of Choice for Bipolar Disorder?

It is encouraging to see this excellent Psychology Today piece on the safety and efficacy of lithium in the treatment of bipolar disorder.  Indeed, lithium might be considered the drug of choice in all mood disorders, because they all seem to be part of the same package — a package that German psychiatrist Emil Kraepelin labeled “manic-depressive insanity.”  And if lithium works for one piece of the package, there is no reason to think it might not be effective for other pieces, as well.